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Results for search "Clinical Trials".
02 Oct
Lead in Consumer Products Remains a Danger to Kids, New Study Finds
Despite years of success in lowering lead exposure, researchers say the toxic metal is still a main source of elevated blood lead levels in children.
Health News Results - 99
01 Oct
Drug Industry Taking Bigger Role in Clinical Cancer Trials
- Carole Tanzer Miller HealthDay Reporter
- October 1, 2024
- Full Page
Clinical trials sponsored by Big Pharma enrolled eight times as many patients as U.S.-government trials did between 2018 and 2022, new research shows.
The study -- conducted by researchers at Fred Hutch Cancer Center in Seattle -- underscores the lack of investment in fe...
14 Jun
Just 1 in 20 Animal Studies Yield Treatments That Make it to Humans
- Dennis Thompson HealthDay Reporter
- June 14, 2024
- Full Page
Animal studies are often considered a first step in finding new drugs and treatments for human diseases, but a new review has discovered that precious few actually produce real-world therapies.
Only 5% of therapies tested in animals wind up being approved by regulators f...
19 Apr
One Neurological Factor Keeps Black, Hispanic Patients From Alzheimer's Clinical Trials
- Dennis Thompson HealthDay Reporter
- April 19, 2024
- Full Page
Black and Hispanic patients with Alzheimer's disease are greatly underrepresented in clinical trials, even though they're more likely to get dementia than whites.
However, racial discrimin...
03 Apr
1 in 5 U.S. Cancer Patients Join in Medical Research
- Dennis Thompson HealthDay Reporter
- April 3, 2024
- Full Page
More patients these days are taking part in cancer research, a new study finds.
At least one in five people with cancer (22%) participate in some form of clinical research, when all types of cancer studies are considered, researchers found.
Moreover, enrollment in ...
10 Oct
Experimental Drug Could Rein in Epilepsy Seizures
- Steven Reinberg HealthDay Reporter
- October 10, 2023
- Full Page
For people with tough-to-treat epilepsy, seizures can be both frightening and dangerous, but a new experimental pill may bring significant relief to over one-third of them.
Dubbed XEN1101, the new drug reduced the frequency of seizures by more than 50%, or even eliminate...
05 Oct
Ketamine Nasal Spray Shows Promise Against Tough-to-Treat Depression
- Amy Norton HealthDay Reporter
- October 5, 2023
- Full Page
A nasal spray containing a ketamine derivative appears to beat one of the standard drugs used for people with difficult-to-treat depression, a new clinical trial has found.
The trial, of nearly 700 people with treatment-resistant depression, found that esketamine nasal s...
04 Oct
Stem Cell Therapy Could Be Breakthrough Against Type 1 Diabetes
- Denise Mann HealthDay Reporter
- October 4, 2023
- Full Page
People with type 1 diabetes lack functional islet cells in their pancreas to produce the hormone insulin and must take daily insulin via injections or a continuous pump to compensate.
20 Jul
Experimental Shot Given Every Six Months Controlled High Blood Pressure in Early Trial
- Denise Mann HealthDay Reporter
- July 20, 2023
- Full Page
Every day, millions of people must take one or more pills to control their blood pressure and reduce their risk for heart attack or stroke, but if new research pans out, some may be able to scrap their pills for a twice-yearly shot with the same benefits.
Given as a shot...
17 Jul
Experimental Alzheimer's Drug Slows Thinking Declines in Late-Stage Trial
- Robin Foster HealthDay Reporter
- July 17, 2023
- Full Page
Another experimental drug meant to slow the damage of Alzheimer's appears poised to join a growing arsenal of new treatments for this memory-robbing disease.
13 Jul
Low-Dose Eyedrops No Better Than Placebo for Nearsightedness Among Kids
- Dennis Thompson HealthDay Reporter
- July 13, 2023
- Full Page
Low doses of the eyedrops ophthalmologists use to dilate your pupils during an eye exam are not able to slow the progression of nearsightedness (myopia) in children, a new clinical trial has found.
Atropine eyedrops at a concentration of 0.01% did not outperform placebo ...
06 Jul
FDA Gives Full Approval to Alzheimer's Drug Leqembi
- Robin Foster HealthDay Reporter
- July 6, 2023
- Full Page
The U.S. Food and Drug Administration on Thursday gave full approval to the Alzheimer's drug Leqembi, clearing the way for insurance coverage of the pricey drug.
"The full FDA approval will open the floodgates for people with early Alzheimer's to get this drug. It's a bi...
27 Jun
New Competitor to Wegovy Shows Promise in Clinical Trials
- Dennis Thompson HealthDay Reporter
- June 27, 2023
- Full Page
An experimental drug appears to outperform the trendy medications Wegovy and Ozempic for both weight loss and diabetes control, a pair of early clinical trials shows.
Retatrutide helped people with obesity drop about one-quarter of their starting weight, on average, duri...
12 Jun
Antibody Treatment Could Fight Rare But Deadly Bile Duct Cancers
- Dennis Thompson HealthDay Reporter
- June 12, 2023
- Full Page
Patients with bile duct cancer might soon have an additional treatment available to them, thanks to a newly discovered tumor target.
Some bile duct cancers are driven by a mutated HER2 gene, which has also been implicated in cancers of the breast, esophagus and prostate,...
12 Jun
More Evidence Gene Therapy Might Cure Sickle Cell Disease
- Cara Murez HealthDay Reporter
- June 12, 2023
- Full Page
A clinical trial that's attempting to discover a cure for sickle cell disease has found a new gene therapy to be safe and successful in four patients.
Two of the patients were treated at Cleveland Clinic Children's in Ohio, and doctors there are hopeful that their positi...
09 Jun
Diabetes Med Metformin Might Help Prevent Long COVID
- Dennis Thompson HealthDay Reporter
- June 9, 2023
- Full Page
A safe, generic diabetes pill can help people avoid long COVID, a new clinical trial shows.
Metformin cut the risk of long COVID by about 40% for patients who received a two-week course of the drug while battling their infection, the researchers reported.
The ...
07 Jun
Patients With Bladder Cancer May Avoid Removal of Extra Lymph Nodes, Study Finds
- Amy Norton HealthDay Reporter
- June 7, 2023
- Full Page
For years, doctors have thought that a more extensive surgery that removes a wider swath of lymph nodes was the best option for certain patients with bladder cancer. Now, a new clinical trial is upending that belief.
Researchers found that the strategy -- known as exten...
06 Jun
Gene-Targeted Drug Tagrisso Cuts Death Rate in Half for Patients With Early-Stage Lung Cancer
- Ernie Mundell HealthDay Reporter
- June 6, 2023
- Full Page
Once-a-day use of the targeted cancer pill Tagrisso (osimertinib) cut the five-year death rate in half for a subset of patients with early-stage lung cancer, a new clinical trial shows.
The results could have major implications for patients whose cancers carry a mutation...
06 Jun
Could a Nitroglycerin Patch Ease Hot Flashes?
- Cara Murez HealthDay Reporter
- June 6, 2023
- Full Page
A new study on using nitroglycerin patches to help women with frequent hot flashes caused by menopause has delivered mixed results.
The benefits of wearing these patches -- long used as chest pain medication -- were modest. They also were short-lived, with any benefits ...
05 Jun
New Drug Could Be Advance Against Glioma Brain Tumors
- Dennis Thompson HealthDay Reporter
- June 5, 2023
- Full Page
An experimental targeted therapy can dramatically slow the progress of common slow-growing brain cancers, a new clinical trial finds.
The oral drug vorasidenib nearly tripled progression-free survival in patients with grade 2 gliomas compared to placebo, nearly 28 months...
02 Jun
Is a Liver Dialysis Device on the Horizon?
- Dennis Thompson HealthDay Reporter
- June 2, 2023
- Full Page
A new liver dialysis device might soon be able to save patients on the edge of death from liver failure, early clinical trial results show.
The DIALIVE device safely improved organ function and alleviated symptoms in patients with acute-on-chronic liver failure, compared...
02 Jun
Software Bias Misses Lung Problems in Black Men, Study Finds
- Cara Murez HealthDay Reporter
- June 2, 2023
- Full Page
A common test for lung function may be missing lung problems in Black men, leading to under-diagnosis and insufficient care.
A new study from the University of Pennsylvania estimates that as many as 40% more Black male patients would have been diagnosed with breathing ...
26 Apr
New Form of Levodopa Might Improve Parkinson's Care
- Dennis Thompson HealthDay Reporter
- April 26, 2023
- Full Page
An extended-release version of a Parkinson's disease drug could provide more stable relief for patients with the movement disorder, new clinical trial data show.
The new formulation of levodopa, called IPX203, extended the duration of patients' "on time" -- the amount of...
13 Apr
Blood Donors' Gender Doesn't Affect Outcomes for Recipients
- Cara Murez HealthDay Reporter
- April 13, 2023
- Full Page
Whether the gender of a blood donor could affect the recipient's survival was an unanswered question in medicine. Until now.
"Some observational studies had suggested female donor blood might be linked with a higher risk of death among recipients compared to male donor b...
03 Apr
Drug Combo Shows Promise Against Advanced Head and Neck Cancer
- Dennis Thompson HealthDay Reporter
- April 3, 2023
- Full Page
An experimental targeted drug could provide a fresh chance for people with recurring head and neck cancer that has grown resistant to other treatments, a new clinical trial says.
Ficlatuzumab used in combination with the already approved targeted drug cetuximab (Erbitux)...
31 Mar
Monthly Injections Might Lower Bleeding in People With Hemophilia
- Dennis Thompson HealthDay Reporter
- March 31, 2023
- Full Page
An experimental injectable drug appears effective in reducing bleeds in patients with hemophilia A and B, according to a pair of new clinical trials.
Two-thirds of people with treatment-resistant hemophilia who were treated with the drug fitusiran had no bleeds at all af...
30 Mar
Doctors Convert Veins Into Arteries to Spare Patients Amputations
- Dennis Thompson HealthDay Reporter
- March 30, 2023
- Full Page
Cynthia Elford had recently lost her left leg to type 1 diabetes, after a sunburned big toe turned nearly black and forced an amputation.
Now, Elford was being told the same thing was happening in her right leg.
"I went to clip the toenail on the big toe of my righ...
20 Mar
New Drug Could Be Treatment Option for People With Eczema
- Dennis Thompson HealthDay Reporter
- March 20, 2023
- Full Page
Patients could soon have access to a new injectable drug to treat atopic dermatitis, the most common form of eczema.
The drug, lebrikizumab, proved effective in teenagers and adults in two clinical trials just published in the
06 Mar
Though Often Prescribed, Diuretic Pills May Not Prevent Kidney Stones
- Amy Norton HealthDay Reporter
- March 6, 2023
- Full Page
A new study is raising questions about the effectiveness of medications long used to prevent painful kidney stones, but experts say there's no reason for patients to toss their prescriptions out at this point.
Anyone who has ever passed a kidney stone would prefer to avo...
09 Feb
'Neuroprotectant' Drug Could Boost Outcomes After a Stroke
- Denise Mann HealthDay Reporter
- February 9, 2023
- Full Page
Using a "neuroprotectant" drug alongside the standard surgical removal of a clot may slash the risk of death and disability following a stroke, a new study finds.
The new medication, called ApTOLL, shields brain tissue from continuing damage by cooling down inflamma...
09 Feb
New Injected Drug May Prevent Severe COVID
- Dennis Thompson HealthDay Reporter
- February 9, 2023
- Full Page
A single injection of an experimental biologic drug may cut in half your risk of hospitalization from COVID-19 infection, new clinical trial results show.
Pegylated lambda interferon (PEG-lambda) proved effective against all COVID-19 variants encountered in this internat...
06 Feb
Targeted Drug Tagrisso Could Be Advance Against Lung Cancer
- Dennis Thompson HealthDay Reporter
- February 6, 2023
- Full Page
The best treatment for a genetically driven form of lung cancer continues to show lasting benefits, a new clinical trial update shows.
Tagrisso (osimertinib) nearly doubles disease-free survival in earlier-stage patients whose lung cancer is driven by a mutation in their...
06 Jan
FDA Approves Second Alzheimer's Drug, Despite Safety Concerns
- Ernie Mundell HealthDay Reporter
- January 6, 2023
- Full Page
The U.S. Food and Drug Administration on Friday approved a second Alzheimer's drug, lecanemab, despite reports of rare brain bleeds linked to use of the drug in some patients.
However, the FDA pointed to the drug's benefits, as well.
"Alzheimer's disease immeasura...
05 Jan
Patients, Doctors Await FDA Decision on Experimental Alzheimer's Drug
- Ernie Mundell HealthDay Reporter
- January 5, 2023
- Full Page
Lecanemab: It's an experimental medication that's been shown in trials to slow cognitive decline in people with Alzheimer's disease.
It's also up for accelerated approval by the U.S. Food and Drug Administration, with a decision expected by Jan. 6.
However, the d...
08 Dec
Antibody Drug Boosts Survival for Type of Advanced Breast Cancer
- Dennis Thompson HealthDay Reporter
- December 8, 2022
- Full Page
A relatively new drug is boosting survival rates for women with a specific type of advanced breast cancer who haven't responded to other treatments, according to a pair of clinical trials.
The targeted antibody drug -- trastuzumab deruxtecan (T-DXd, sold under the b...
29 Nov
Second Death in Trial of Experimental Alzheimer's Drug Is Raising Concerns
- Dennis Thompson HealthDay Reporter
- November 29, 2022
- Full Page
Two people have now died from brain hemorrhages that may be linked to an experimental Alzheimer's drug, calling into question the medication's safety.
A 65-year-old woman with early-stage Alzheimer's recently died from a massive brain bleed that some researchers link to ...
07 Nov
Amid a Surge in RSV Cases, Hopes for a New Vaccine
- Dennis Thompson HealthDay Reporter
- November 7, 2022
- Full Page
Infants and children sick with RSV are flooding pediatricians' offices and children's hospitals across the United States, due to an early surge of the common childhood virus this year.
But within one or two "sick seasons,"doctors expect to have on hand long-sought tools ...
04 Nov
Clinical Trials Could Help Stop Alzheimer's. But Who Will Join Them?
- Cara Murez HealthDay Reporter
- November 4, 2022
- Full Page
New drugs that could slow or prevent the start of dementia would be groundbreaking, but a new poll suggests many middle-aged adults may be reluctant to take part in the studies that test those medications.
Only about 12% of the roughly 1,000 people aged 50 to 64 who were...
26 Oct
Pain Relief in a FLASH: Radiation Treatments Lasting Seconds May Advance Cancer Care
- Steven Reinberg HealthDay Reporter
- October 26, 2022
- Full Page
Flash radiotherapy, a new technology that uses targeted proton beams, is safe and effective in relieving pain for terminal cancer patients, a new, small study suggests.
...
17 Oct
Major Trial of Monkeypox Treatment TPOXX to Launch in Africa
- Dennis Thompson
- October 17, 2022
- Full Page
The ability of TPOXX to treat people infected with monkeypox is being directly tested in a new clinical trial in central Africa, U.S. health officials have announced.
TPOXX -- th...
10 Oct
Drug Shows Promise Against Autoimmune Disease Scleroderma
- By Cara Murez HealthDay Reporter
- October 10, 2022
- Full Page
Researchers report early success with using an existing rheumatoid arthritis (RA) drug to treat systemic sclerosis, a rare but potentially devastating autoimmune condition.
Th...
03 Oct
Alzheimer's Meds Are Mostly Tested in Whites. That Worries Black Patients, Caregivers
- Sydney Murphy HealthDay Reporter
- October 3, 2022
- Full Page
Larry Griner resigned from his job in California and moved back to his childhood home in Baltimore nearly five years ago so he could care for his mother, Norma.
28 Sep
New Alzheimer's Drug Shows Promise in Phase 3 Clinical Trial
- By Ernie Mundell HealthDay Reporter
- September 28, 2022
- Full Page
Japanese drugmaker Eisai on Wednesday said its experimental drug lecanemab helped slow thinking declines among people in the early stages of Alzheimer's disease.
The findings from a phase 3...
12 Sep
Screening Test Leads to Fewer Women Included in Autism Studies
- By Sydney Murphy HealthDay Reporter
- September 12, 2022
- Full Page
A frequently used screening test for autism creates a gender gap that could hinder diagnosis an...
08 Sep
Experimental Drug Shows Promise Against Lupus
- Denise Mann HealthDay Reporter
- September 8, 2022
- Full Page
An experimental drug that has been shown to treat rashes in people with lupus may also help with lupus-related joint pain.
Affecting as many as 1.5 million people in the United States, lupus is an autoimmun...
25 Aug
New MS Treatment Shows Promise in Trial
- Amy Norton HealthDay Reporter
- August 25, 2022
- Full Page
An experimental antibody therapy for multiple sclerosis can cut symptom flare-ups by half, versus a standard treatment, a new clinical trial has found.
The drug, called ublituximab, be...
25 Aug
Pill to Counter Lupus Shows Promise in Mouse Study
- By Dennis Thompson HealthDay Reporter
- August 25, 2022
- Full Page
An experimental new pill could boost treatment of the autoimmune disease lupus, researchers reported at the American Chemical Society's annual meeting.
The pill has been shown in mouse studies to inhibit lupus symptoms, reverse signs of organ damage, and prevent death, <...
23 Jun
Women Still Underrepresented in Many Clinical Trials
- By Cara Murez HealthDay Reporter
- June 23, 2022
- Full Page
To ensure that all kinds of patients get drugs and devices that are safe and effective for them, they need to be represented in clinical trials, but a new study shows that
15 Jun
Cancer Clinical Trials Make Comeback After Pandemic Slowdown
- By Robert Preidt HealthDay Reporter
- June 15, 2022
- Full Page
Cancer clinical trials in the United States appear to be rebounding after a significant slowdown during the pandemic, researchers say.
For the study, the investigators analyzed da...
06 Jun
New Weight-Loss Drug Looks Good in Trial
- Denise Mann HealthDay Reporter
- June 6, 2022
- Full Page
A newly approved drug for type 2 diabetes may be a game-changer for treating obesity, too.
Given as a shot once a week, tirzepatide works on two naturally occurring hormones that help tell the brain that you are full. It may be as effective as weight-loss surgery.
...
06 Jun
In Small Study, New Treatment Brings Remission of Rectal Cancer in All Patients
- By Robert Preidt HealthDay Reporter
- June 6, 2022
- Full Page
A small study delivers startling results on the power of a new immunotherapy treatment against rectal cancer: The drug triggered remission in all the patients who got it.
...