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Stroke rates continue to rise among adults and children living with sickle cell disease, despite new standards of care meant to lower their risk, a new study fin...
A drug called hydroxyurea has long been used to fight sickle cell disease, but some female patients may have shied away from it due to concerns that it could harm future fertility.
Those fears may be unfounded: A n...
Women who've undergone stem cell treatments for blood cancers, or for illnesses such as sickle cell disease, can successfully bring a pregnancy to term, new research shows.
The German findings run counter to the perceived wisdom on this issue: Many such patients...
There's more good news in the battle against sickle cell disease, with another trial finding CRISPR gene-editing therapy delivering impressive results for patien...
Sickle cell disease is one of many chronic health conditions that dramatically increases the risk of hospitalization and death in people infected by COVID-19.
Unfortunately, folks with sickle cell disease are much less likely to have received the best protection availabl...
The U.S. Food and Drug Administration on Friday approved two milestone gene therapies for sickle cell disease, including the first treatment ever approved that uses gene-editing technology.
Casgevy, developed by Vertex Pharmaceuticals of Boston and CRISPR Therapeutics of...
A type of gene therapy that precisely "edits" a key bit of DNA might offer a new way to treat sickle cell disease -- a painful inherited condition that largely strikes Black children and adults.
A clinical trial that's attempting to discover a cure for sickle cell disease has found a new gene therapy to be safe and successful in four patients.
Two of the patients were treated at Cleveland Clinic Children's in Ohio, and doctors there are hopeful that their positi...
An exceptionally pricey gene therapy cure for sickle cell disease could soon be available, but it's not clear whether insurance companies will balk at the cost and deny coverage.
On the surface, the gene therapy does not appear as cost-effective as the grinding medical c...
While joint reconstruction surgeries are fairly common, they may be anything but routine for people with sickle cell disease.
Patients with the blood disorder who undergo total knee replacement are at a higher risk for complications than other patients, according to a ne...
Too few children with sickle cell anemia are getting the recommended screening tests for stroke, a common complication of this disease, a new government report finds.
W...
Folic acid, a B vitamin that's used widely to fortify foods and lower the risk of birth defects, may carry a hidden risk for those who have to take huge quantities of it: A new study shows those folks were more likely to get COVID-19 and to die from it.
"We examined whet...
A network that receives and supplies blood for transfusions nationwide is calling for more diverse blood donors.
Less than 20% of blood donations are from people of color, but those donations are essential. Frequently transfused patients often require blood from donors w...
Americans with sickle cell disease who have private insurance face average out-of-pocket costs of $1,300 a year and a lifetime total of $44,000, new research reveals.
That means that their out-of-pocket expenses are nearly four times higher compared to people without the...
People with sickle cell disease who take corticosteroids to treat asthma or inflammation may suffer severe pain and even need to be hospitalized, researchers report.
This reaction to corticosteroids can be particularly severe among older people, women and patients not ta...
A gene therapy that could provide a permanent cure for sickle cell disease continues to show success through a third wave of patients, researchers report.
The therapy, LentiGlobin, restored normal blood function in 35 sickle cell patients who had the one-time procedure, ...
Treating sickle cell anemia with the drug hydroxyurea may also reverse related heart abnormalities, a new study suggests.
Heart issues are common among people with sickle cell disease. Among them are enlargement of the heart and an impaired ability to relax heart muscles...