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11 Oct
A new study finds 43% of people with Long COVID symptoms still have SARS-CoV-2 proteins circulating in their blood 1 to 14 months after testing positive.
Gene therapy could help obese kids avoid health problems associated with excess weight, including arthritis, a new, preliminary study in mice suggests.
The gene therapy prompts...
Most boys treated with breakthrough gene therapy for a rare but deadly brain illness are faring well six years later, two new reports find.
The 77 boys were treated for cerebral adrenoleukodystrophy (CALD), a formerly incurable and progressive genetic brain disease that ...
A new gene therapy approved earlier this year can serve as a sustainable single-dose treatment for people with hemophilia B, newly published clinical trial data shows.
People with hemophilia B saw their bleeding episodes drop by an average 71% following a single infusion...
Gene therapy may restore vision to children and adults robbed of their sight by a rare inherited condition called Leber congenital amaurosis, researchers report.
The illness is caused by mutations in the GUCY2D gene, which is critical to producing proteins that enable vi...
There's more good news in the battle against sickle cell disease, with another trial finding CRISPR gene-editing therapy delivering impressive results for patien...
Chlidren born deaf have had their hearing restored in both ears as a result of gene therapy, a new study reports.
All five children showed hearing recovery in both ears, with dramatic improvements in speech perception and the ability to locate the position of a sound.
An experimental gene therapy could one day provide a first-ever cure for genital and oral herpes, researchers report.
The gen...
Opal Sandy was born into a world she could not hear.
The British baby girl, now 18 months old, had a rare genetic condition called auditory neuropathy that interrupted nerve impulses that travel from the inner ear to the brain. She'd been fitted with a cochlear imp...
An injectable gene therapy caused measurable improvements in vision among a small group of people with inherited blindness, an early-stage clinical trial says.
Researchers recruited 14 people with Leber Congenital Amaurosis (LCA), a rare genetic condition that causes bab...
Five of six Chinese children born deaf due to a rare genetic defect now have the ability to hear, thanks to an experimental gene therapy.
The therapy involved a hollowed-out virus loaded with a healthy version of the gene responsible for producing otoferlin, a protein ne...
The U.S. Food and Drug Administration on Friday approved two milestone gene therapies for sickle cell disease, including the first treatment ever approved that uses gene-editing technology.
Casgevy, developed by Vertex Pharmaceuticals of Boston and CRISPR Therapeutics of...
MONDAY, Nov. 13, 2023 (Healthday News) -- Two new gene-editing treatments that target dangerously high levels of cholesterol in people with a genetic predisposition to the condition were found safe and effective in new, groundbreaking research.
While powerful drugs like ...
Gene therapy has restored mobility in mice with completely severed spinal cords, researchers report.
The mice regained the ability to walk, with gait patterns resembling those of mice that resumed walking naturally after only partial cord injuries, the investigators foun...
A second human patient has received a genetically altered pig heart as he battles the ravages of end-stage heart disease.
The 58-year-old man, Lawrence Faucette, received the pig organ at the University of Maryland Medical Center in Baltimore.
The medical team was ...
A type of gene therapy that precisely "edits" a key bit of DNA might offer a new way to treat sickle cell disease -- a painful inherited condition that largely strikes Black children and adults.
For people with severe alcohol use disorder, a new gene therapy trial could lead to an effective treatment that would involve chemically rebalancing the area of the brain associated with addiction.
"With alcohol alone, there's generally more than 100,000 deaths [in the ...
Two new studies using CRISPR gene editing offer potential new treatments for Alzheimer's disease.
"A pipeline of potential new treatments offers hope for the Alzheimer's and dementia community,"said
A clinical trial that's attempting to discover a cure for sickle cell disease has found a new gene therapy to be safe and successful in four patients.
Two of the patients were treated at Cleveland Clinic Children's in Ohio, and doctors there are hopeful that their positi...
Millions of stray cats roam the world over, and surgical sterilization has long been the primary method of population control.
But a small new study shows promising results for a one-and-done contraceptive injection.
Researchers say this first-of-its-kind appr...
An exceptionally pricey gene therapy cure for sickle cell disease could soon be available, but it's not clear whether insurance companies will balk at the cost and deny coverage.
On the surface, the gene therapy does not appear as cost-effective as the grinding medical c...
"Zinc fingers"might sound like the world's worst candy bar, but these human proteins might prove key to treating complex genetically driven diseases.
A new artificial intelligence program is poised to enable the simple production of zinc fingers, according to
Ten children with an especially rare and hard-to-treat form of "bubble boy" disease are living normal lives after receiving a new gene therapy approach, researchers say.
Experts said the findings are a major advance for children with the disease -- a subtype of seve...
Patients with a high-risk bladder cancer now have a new option to treat it.
The U.S. Food and Drug Administration on Friday approved a gene therapy called Adstiladrin, which is designed to work for patients who have what's called high-risk non-muscle-invasive bladder can...
An experimental gene therapy that's applied as a skin gel appears to heal wounds caused by a rare and severe genetic skin disease.
Experts called the findings "remarkable," and said they bring hope of a better quality of life to children and young adults living with the ...
People with one form of the genetic blood disorder hemophilia now have a one-time treatment with a $3.5 million price tag.
The U.S. Food and Drug Administration approved the new gene therapy Hemgenix on Nov. 22. Soon after, drugmaker CSL Behring revealed its cost.
Doctors are hopeful that an innovative treatment performed before birth may help children born with the rare genetic, and often fatal, condition called Pompe disease.
A thriving Canadian toddler is evidence that treatment while still in the womb offers better outcomes.
Gene editing has for the first time produced modified immune cells finely honed to target and attack cancer cells, researchers say.
A team used the gene editing tool CRISPR to alter immune cells drawn from 16 patients who had a variety of solid cancers, including colon, ...
An experimental gene therapy offers hope for rapid improvement in the night vision of adults who have a congenital form of childhood-onset blindness, researchers report.
In this ongoing...
People with hemophilia B could find their bleeding risk dramatically reduced with just one injection of an experimental gene therapy, a new study reports.
Hemophilia B is a rare and inherited ...
An experimental gene therapy for spinal cord pain shows promise in mice, researchers say.
About half of spinal cord injury patients have neuropathy, which is chronic or debilitating pain, tingling, numbn...
An experimental cream-based gene therapy may soon become the first U.S. government-approved means for treating a rare and devastating skin disease that produces "butterfly children."
Science could be well on its way to a cure for type 1 diabetes, as researchers hone transplant therapies designed to restore patients' ability to produce t...
Scientists who conducted the first gene editing in ticks say this line of research could lead to new ways to reduce tick-borne diseases in humans.
For countless teens, it's the scourge of adolescence. But researchers say the discovery of new genetic variants associated with acne could help doctors identify people at high risk and perhaps point the way to new treatments.
"Despite major treatment advances in other sk...
More than 10 years after Doug Olsen underwent an experimental gene therapy that turned his T-cells into cancer killers, his leukemia
A gene therapy that could provide a permanent cure for sickle cell disease continues to show success through a third wave of patients, researchers report.
The therapy, LentiGlobin, restored normal blood function in 35 sickle cell patients who had the one-time procedure, ...
Gene therapy shows promise in reducing, and even halting, potentially life-threatening bleeding events in people with hemophilia, researchers report.
Hemophilia A is the most common inherited bleeding disorder, affecting one in 5,000 males worldwide. It's caused by a mis...
Gene therapy might soon offer a new option for children with a rare genetic disorder that damages tissues throughout the body, researchers are reporting.
In a study of eight children with the condition, called Hurler syndrome, researchers found that the gene therapy was ...
An experimental gene therapy to boost the effectiveness of the Parkinson's drug levodopa yielded promising results in mice, researchers report.
As the loss of dopamine-releasing neurons advances in late-stage Parkinson's, levodopa is less able to ease movement problems c...
Nine of 10 patients with so-called "bubble boy" immune disease who received gene therapy about a decade ago are still disease-free, researchers report.
The gene therapy was developed at the University of California, Los Angeles (UCLA), to treat the rare and deadly immune...
Multiple sclerosis (MS) patients undergoing a treatment that depletes a type of immune cell that fuels MS attacks still have a strong response to mRNA COVID-19 vaccines, a new study finds.
"The message from this study is clear -- it is worthwhile for patients with MS rec...